Biotechnology and Human Health

Lettuce Could Protect Astronauts’ Bones on Mars Trip

Astronauts might one day grow and eat genetically modified plants to ward off disease associated with long spaceflights. Researchers at the College of Engineering have developed a transgenic, or genetically modified, lettuce producing a drug to protect against bone density loss in microgravity. Kevin Yates, a graduate student working with Professor Karen McDonald and Adjunct Professor Somen Nandi at the UC Davis Department of Chemical Engineering, developed the lettuce that expresses a fusion protein combining PTH with part of a human antibody protein. The fusion protein is designed to be stable in the bloodstream and to allow astronauts to potentially purify the drug from plant extracts, Nandi said.